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KMID : 1059520110550020243
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Journal of the Korean Chemical Society
2011 Volume.55 No. 2 p.243 ~ p.250
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Synthesis and Antibacterial Activity of Novel 5-(heteroaryl)isoxazole Derivatives
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RamaRao, R. Janaki
Rao, A.K.S. Bhujanga
Sreenivas, N.
Kumar, B. Suneel
Murthy, Y. L. N.
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Abstract
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The synthesis, characterization and antibacterial activity of novel isoxazole derivatives were reported. 3-Di (alkylamino)acryloalkanones were prepared and used as synthons to get the target isoxazole derivatives via reaction with hydroxylamine hydrochloride or hydroxylamine-O-sulphonic acid.
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KEYWORD
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Isoxazole derivatives, 3-di(alkylamino)acryloalkanones, Hydroxylamine hydrochloride, Hydroxylamine-O-sulphonic acid, Antibacterial activity
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